For authors

Article Types

Each evidence-synthesis format has its own reporting, protocol, methodological and supplementary-material requirements. Word counts exclude the abstract, references, tables, figure legends and supplementary files.

Systematic Review

Main text
Up to 6,000 words
Abstract
Up to 250 words
Keywords
3–6 MeSH terms
Tables and figures
Normally up to 8 combined tables and figures
References
Minimum 30; no upper limit when justified

Protocol

Describe the protocol and any registration in the manuscript. Prospective registration in PROSPERO, OSF or another permanent public registry is recommended; no separate protocol upload is required at initial submission.

Reporting guidance

  • PRISMA 2020
  • PRISMA-S
  • PRISMA-P for protocols
  • Applicable PRISMA extension where relevant

Required manuscript sections

  • Title page
  • Structured abstract: Background, Methods, Results, Conclusions
  • Introduction
  • Methods
  • Results
  • Discussion
  • Conclusions
  • Declarations
  • References
  • Tables and figure legends

Methodological expectations

  • Explicit review question and eligibility criteria
  • Complete reproducible searches for every source
  • Independent screening and data extraction
  • Design-appropriate risk-of-bias assessment
  • Pre-specified synthesis methods
  • GRADE or another justified certainty framework where applicable

Supplementary materials

  • Supplementary material is optional at initial submission
  • Upload only material that is necessary to understand or reproduce the review and is not already included in the manuscript

Meta-Analysis

Main text
Up to 6,500 words
Abstract
Up to 250 words
Keywords
3–6 MeSH terms
Tables and figures
Normally up to 8 combined tables and figures
References
Minimum 30; no upper limit when justified

Protocol

Describe the protocol and any registration in the manuscript. Prospective registration in PROSPERO, OSF or another permanent public registry is recommended; no separate protocol upload is required at initial submission.

Reporting guidance

  • PRISMA 2020
  • PRISMA-S
  • PRISMA-NMA for network meta-analysis
  • PRISMA-DTA for diagnostic accuracy
  • PRISMA-IPD for individual participant data

Required manuscript sections

  • Title page
  • Structured abstract: Background, Methods, Results, Conclusions
  • Introduction
  • Methods
  • Results
  • Discussion
  • Conclusions
  • Declarations
  • References
  • Tables and figure legends

Methodological expectations

  • Pre-specified effect measures and outcomes
  • Justification of fixed-effect or random-effects models
  • Assessment of heterogeneity and small-study effects
  • Sensitivity and subgroup analyses
  • Certainty-of-evidence assessment
  • Reproducible analytic code

Supplementary materials

  • Supplementary material is optional at initial submission
  • Upload only material that is necessary to understand or reproduce the analysis and is not already included in the manuscript