TY - JOUR TI - Multimodal and Generative AI-Enabled Clinical Decision Support in Medicine: A PRISMA 2020-Informed Evidence Map and Narrative Synthesis AU - B.N. Sadykov AU - T.M. Saliev AU - K.K. Toguzbaeva AU - G.S. Bismildina AU - A. Tolegenkyzy AU - D.M. Ospanbekova JO - Global Medical Reviews PY - 2026 DA - 2026-07-27 VL - 1 IS - 1 SP - e0003 KW - multimodal artificial intelligence KW - vision-language models KW - generative AI KW - clinical decision support KW - human-in-the-loop KW - external validation KW - equity AB - Background: Multimodal and generative AI systems are increasingly proposed for clinical decision support, but the literature ranges from pragmatic trials to simulated consultations and benchmark-like evaluations. Objective: To identify and synthesize empirical clinical and near-clinical evidence while keeping strict multimodal AI evidence separate from adjacent text-based generative AI clinical decision-support studies. Methods: A structured, PRISMA 2020-informed evidence map and narrative synthesis covered clinician-facing studies published from 2018 to 9 July 2026. Results: Seventeen empirical studies were included: 12 in the strict multimodal core and five in an expanded contextual set. Patient-important outcome evidence remained limited. Conclusions: The evidence supports assistive, auditable, human-in-the-loop use for triage, documentation, decision preparation, second reading, and specialist workflow support. Autonomous deployment is not supported. UR - https://glr.sciences.kz/article/multimodal-generative-ai-clinical-decision-support L2 - https://glr.sciences.kz/downloads/GMR_2026_1_1_e0003_multimodal-generative-ai-clinical-decision-support.pdf ER -